Chess is a strategic board game played by characters in Cheyenne.
- Cheyenne played chess nearly every day while holed up with a Russian during one winter. Johnny Bravo
- Cheyenne and Matt Crowley played a few rounds of chess during Cheyenne's recuperation after he was beat up by Ben Taggert and his thugs. Johnny Bravo
- Nick Avalon beat Marshal Cheyenne at chess while he waited in jail to be hung for murdering Lee Quillan. Trial By Conscience
- Captain Duquesne referenced chess when he decided to "sacrifice a pawn", in this case the pawn was Trooper Jerry Dailey. Lone Patrol